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Blood Pressure Brain Health Inflammation Uncategorized

Resistant blood pressure linked to surprising cause of brain inflammation

Resistant blood pressure linked to surprising cause of brain inflammation
A large group of prescription medication bottles sit on a table as a man in the background stands with his hand on his head. The image is photographed with a very shallow depth of field with the focus being on the pill bottles in the foreground.

My mother had high blood pressure, and I’ve inherited it from her.

Naturally, I’m conscientious about salt in my diet. I don’t even own a saltshaker! And I take a daily pill that keeps my blood pressure under control.

I’m one of the lucky ones. For many people with hypertension, medication is not effective. And until now, the reason for this was a mystery.

Science has always believed that hypertension begins in the kidneys, and medications are based on this assumption.

However, new brain imaging techniques are now proving that we’ve got it all wrong…

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Too much salt may inflame the brain

It’s commonly thought that hypertension begins in the kidneys, which filter blood to regulate the amount of sodium and water in the body.

When blood pressure rises, the kidneys excrete more sodium and water to reduce blood volume and lower pressure.

High blood pressure also damages the delicate blood vessels in the kidneys, triggering the release of the hormone renin, which in turn causes hypertension. Thus, a vicious cycle occurs.

But now we’re learning that when high blood pressure is resistant to treatment, it may be that the drugs are aimed at the wrong organ and the wrong hormone.

Researchers at McGill University in Montreal have discovered that cases of drug-resistant hypertension may originate not in the kidneys but in the brain.

They gave rats a solution of water and two percent salt. This is comparable to a daily diet high in fast food and processed foods like bacon.

The high-salt diet activated immune cells in a specific brain region, leading to inflammation and a surge in another hormone, vasopressin, which also increases blood pressure.

The researchers used rats instead of the more commonly studied mice because rats regulate salt and water more like humans. That makes the findings more likely to apply to people, noted lead author Prof. Masha Prager-Khoutorsky.

“This is new evidence that high blood pressure can originate in the brain, opening the door for developing treatments that act on the brain,” says Prof. Prager-Khoutorsky.

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Avoid triggers that raise blood pressure

Giving up salt can be difficult, but an alternative that most people don’t know about is potassium-enriched salt.

It looks the same as traditional salt (sodium chloride), except some of the sodium chloride has been replaced with potassium chloride.

Not only does this salt help reduce your sodium intake, but potassium also works to strengthen your heart muscles.

But in light of this new connection between the brain and inflammation, lowering inflammation should be addressed.

A safe and easy way to do that is by adding omega-3s to your diet by eating fatty fish weekly or supplementing.

An analysis published in the Journal of the American Heart Association has identified the optimal daily amount of omega-3s needed to lower blood pressure.

However, hidden sources of sodium can sabotage all of these efforts. Be sure to check labels, especially on condiments and processed foods.

Finally, another one that most people don’t know: not all hypertension triggers are edible. Other proven hypertension triggers include:

  • Loneliness
  • Sleep apnea
  • Thyroid problems
  • Antidepressants
  • Holding on to a full bladder
  • Cold and migraine medications

I hope the information I’ve given you here has provided some good ammunition against hypertension.

Editor’s note: What do you really know about stroke? The truth is, only 10% of stroke survivors recover almost completely, and all doctors can offer is what to do after a stroke occurs. That’s unacceptable considering 80% of strokes are preventable! Click here to discover how to escape The Stroke Syndrome: 5 Signs it’s Stalking You — Plus the Hidden Causes and Preventive Measures You’ve Never Heard About!

Sources:

Too much salt can hijack your brain — Science Daily

Microglia regulate neuronal activity via structural remodeling of astrocytes — Neuron

Categories
Circulation Heart Health Inflammation Oral Health Uncategorized

How your dentist can keep your arteries from narrowing

How your dentist can keep your arteries from narrowing
Dental and health medical concept. Frustrated young man touching his cheek and keeping eyes closed while sitting on the couch at home. Toothache, medicine, health care concept, Teeth Problem

The TV series Fraiser has always been one of my all-time favorites. It was witty, silly, and the characters were likable yet easy to laugh at.

But my favorite episode offers so much more than a few good laughs…

In it, Frasier’s brother Niles – who, with his fussy tendencies and idiosyncrasies, was always my favorite character – keeps complaining of a throbbing toothache.

His pain turns out to have nothing to do with his tooth itself — but is actually referred heart pain that lands him in cardiac surgery for blocked arteries.

I’m sure it seemed far-fetched to some viewers at the time, but in the years since, studies have demonstrated that certain species of bad bacteria in the mouth can increase inflammatory proteins that accelerate the deposition of buildup in the coronary arteries.

Now, research is revealing that while poor oral health can damage the heart and blood vessels, a focused dental care routine that’s easily accessible could actually reduce narrowing of the arteries over time.

Here’s what you need to know…

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How gum disease leads to thick arteries

Periodontists and cardiologists conducted a gold-standard randomized trial at a dental hospital in central London. They followed 135 people with severe periodontitis (also known as gum disease).

For each person, they took blood samples for markers of inflammation and oxidative stress. They also measured how much the arteries dilated when blood flow increased, a measure of blood vessel functioning, and measured the thickness of their artery walls via ultrasound — a key marker for cardiovascular disease risk.  

The participants were randomly split into separate groups to receive dental care — but it wasn’t the same old standard care for all participants…

  • The first group received “intensive periodontitis treatment,” which included a thorough cleaning of the whole mouth and a deep cleaning below the gum line to remove plaque and tartar.
  • The rest received a regular cleaning — with just a scale and polish — typical of a yearly dental visit.

Then, the participants were followed over the next two years, and each received further dental treatments at regular intervals throughout that time. Researchers also reassessed the carotid artery at the one-year and two-year marks, took blood samples and measured blood-vessel function at five different times.

The results spoke for themselves…

People who went through the intensive periodontitis treatment had:

  • Carotid arteries with much lower thickness levels, indicating a lower risk for heart disease
  • Better blood vessel function
  • Lower levels of inflammatory and oxidative stress markers in their blood, which lead to atherosclerosis

In fact, the benefits patients received from deep gum treatment were “comparable to what has been seen with lifestyle interventions and some pharmacological agents in similar populations,” said Dr. Francesco D’Aiuto, a clinical research periodontist at University College London.

These findings suggest that oral health should be taken seriously as a contributing factor in cardiovascular disease, far more seriously than it has been considered previously, despite past research.

“For many, many years, dentists have been focusing on the teeth, forgetting the rest of the body, and physicians have been focusing on the body, forgetting that there are teeth,” said Dr. Maurizio Tonetti, a clinical and research periodontist. “They are really two worlds that have been separated and need to go back together for the benefit of patients.”

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Making oral health a priority

The good news is, this study proves that when you take care of your teeth and gums, you can support a healthy heart and blood vessels, along with a healthy mouth.

And in addition to seeing your dentist regularly, there are ways to do that at home.

First, be sure to take these six steps for fighting gum disease naturally. They include everything from diet and things to add to your toothpaste to supplements that can help.

I also highly recommend drinking matcha tea or using it in place of your usual mouthwash as it helps take down gum disease-causing bacteria.

I also practice oil pulling, specifically with coconut oil, to leverage a flavonoid known as prunin laurate or Pru-C12. Pru-C12 stops the growth of P. gingivalis, a bacterium frequently detected in deep periodontal pockets, considered to be the most critical bacterium in periodontal disease.

Keep your smile—and your ticker—in tip-top shape!

Editor’s note: Do you know that poor gums and teeth are linked to the number one killer in America? Not to mention kidney disease… rheumatoid arthritis… Parkinson’s disease… depression… and so much more. Click here to discover America’s Hidden Dental Health Crisis: How to protect yourself and your family from this dangerous public health peril!

Sources:

Gum disease treatment slows the thickening of arteries, clinical trial shows – LIVESCIENCE

Categories
Cancer Eye Health Health Supplements Immune System

The eye vitamin joining the fight against cancer

The eye vitamin joining the fight against cancer
Woman smiles while placing vitamin in mouth

Zeaxanthin’s impact on eye health is well-known.

It’s one of the only carotenoids that accumulates in the retina. When taken with the other (lutein), it works to protect your eyes from the harmful free radicals behind macular degeneration.

But there may be a lot more to zeaxanthin than that. In fact, research indicates this plant-derived compound could help protect against one of our most dreaded diseases…

Could zeaxanthin help against cancer?

Building on years of work by the lab of Dr. Jing Chen of the University of Chicago, researchers led by Chen sought to better understand how nutrients influence the immune system.

Zeaxanthin has already demonstrated anti-inflammatory effects. When screening an extensive blood nutrient library, the team identified zeaxanthin as a compound that directly enhances the activity of a certain type of immune cell (CD8+ T cells) that kills tumor cells. CD8+ T cells rely on a structure known as the T cell receptor (TCR) to recognize and destroy abnormal cells.

Upon interacting with cancer cells, the researchers discovered zeaxanthin stabilizes and strengthens the formation of the TCR complex on CD8+ T cells. This, in turn, triggers more robust intracellular signaling that boosts T cell activation, cytokine production and, importantly, tumor-killing ability.

Then, the researchers tested zeaxanthin in mouse models of cancer. Dietary supplementation with zeaxanthin in these mouse models slowed tumor growth. Plus, when combined with immune checkpoint inhibitors — a type of immunotherapy that has transformed cancer treatment in recent years — zeaxanthin significantly enhanced anti-tumor effects compared to immunotherapy alone.

The researchers extended the findings by testing human T cells engineered to recognize specific tumor antigens. They found that treatment with zeaxanthin improved the ability of these cells to kill melanoma, multiple myeloma, and glioblastoma cells in laboratory experiments.

“Our data show that zeaxanthin improves both natural and engineered T-cell responses, which suggests high translational potential for patients undergoing immunotherapies,” Chen says.

To sum up, the researchers discovered in laboratory and mouse studies that zeaxanthin may strengthen the cancer-fighting activity of immune cells as well as boost the effectiveness of cancer immunotherapy.

Chen says the researchers “were surprised” to uncover zeaxanthin’s new function as an immune booster. “Our study shows that a simple dietary nutrient could complement and strengthen advanced cancer treatments like immunotherapy,” he says.

Zeaxanthin’s many benefits and more to come

Clearly, these results are promising. However, the researchers stress that the work is still at an early stage, with most of the findings coming from laboratory and animal studies.

“Our findings open a new field of nutritional immunology that looks at how specific dietary components interact with the immune system at the molecular level,” Chen says. “With more research, we may discover natural compounds that make today’s cancer therapies more effective and accessible.”

Zeaxanthin is naturally found in vegetables like orange peppers, sweet potatoes, spinach and kale. It’s also available in over-the-counter supplements for eye health, with benefits that go far beyond.

It’s inexpensive, widely available and well-tolerated. It also has a known safety profile, which means it can be safely tested as an adjunct (or addition) to cancer therapies.

Although this research is in its early stages, there really are no downsides to adding zeaxanthin-rich foods or a supplement containing zeaxanthin to your diet today. You’ll be protecting your eye health — and potentially giving yourself a boost against cancer as well.

Editor’s note: Discover how to live a cancer prevention lifestyle — using foods, vitamins, minerals and herbs — as well as little-known therapies allowed in other countries but denied to you by American mainstream medicine. Click here to discover Surviving Cancer! A Comprehensive Guide to Understanding the Causes, Treatments and Big Business Behind Medicine’s Most Frightening Diagnosis!

Sources:

Plant-based nutrient can boost immune cells’ ability to fight cancer — Medical Xpress

Zeaxanthin augments CD8+ effector T cell function and immunotherapy efficacy — Cell Reports Medicine

Categories
Liver Health

6 strange signs of liver trouble

6 strange signs of liver trouble
Swollen left foot comparison after wasp sting on female foot area

Fatty liver is a condition where fat builds up in your liver and slowly erodes the organ’s vital functions. A poor diet can contribute, especially one high in fat, but something more sinister is at play as well.

Chemicals and toxins we’re exposed to daily — through personal care products, pesticides in foods, furniture, household items and plastic — disrupt the endocrine system and affect the liver’s normal functions, including its ability to detoxify the bloodstream.

Overwhelmed by chemicals, it becomes less able to break down fats and waste and these poisons get stored in the liver and other parts of the body.

According to doctors at Harvard, it’s an issue that affects 20 percent to 40 percent of the US population.

The reason for the wide variance in estimates is what makes fatty liver so dangerous.

You see, like heart disease, the condition can be a “silent killer” since many people never notice they have an issue until serious — or even irreversible — damage has occurred.

That’s because signs that your liver is struggling can be subtle. However, they can be spotted if you know what to look for.

And even better, catching the symptoms of liver issues early can give you the ability to stop the damage and let your liver heal.

Here are the early symptoms of liver problems to watch out for:

#1 – Swollen ankles

Puffy or bloated ankles could be a sign that your liver is shutting down.

You see, your liver is responsible for making a protein known as albumin. Albumin is what your blood vessels use to prevent fluid from leaking into the surrounding tissue.

However, if your liver is packed with fat and inflamed, it simply can’t function.

Levels of albumin go down and fluid starts seeping from those blood vessels and pooling in your legs, ankles, and abdomen.

#2 – Fatigue

According to a 2019 study, published in the World Journal of Gastroenterology, “The liver is central in the pathogenesis of fatigue because it uniquely regulates much of the storage, release and production of substrate for energy generation.”

In other words, if you’re liver isn’t up to par, your body can’t make the energy it needs to get through the day. And you start feeling drug out, drained, and just plain exhausted.

#3 – Irregular sleep

Liver damage can alter your sleep-wake cycle causing you to fall asleep and stay asleep. And even if you can turn off your mind and slip into dreamland, you might not feel refreshed when you wake up.

Additionally, people with liver issues often have health problems such as diabetes that raise their chances of suffering from insomnia even more.

#4 – More pronounced impact of caffeine

Your liver is the primary organ responsible for metabolizing caffeine.

And studies have found that liver disease can slow caffeine clearance from your body, allowing the effects of that coffee you just drank to linger.

So if you’re a regular coffee drinker and suddenly notice it’s ramping you up much more than usual, pay attention.

#5 – Flushing rising from trunk to head

If your liver is dysfunctional, it can cause your body to overheat.

This happens when your liver is overworked or under pressure, it heats up. This may cause a feeling similar to the hot flashes associated with menopause. And it can even lead to excessive sweating.

#6 – Severe side effects/reactions from medications

Just like with caffeine, your liver has to break down any medications you take.

And according to the Merck Manual (the handbook doctors everywhere turn to when they have a question), “Sometimes alterations (damage to the liver) increase levels of bioavailable drug, causing normal drug doses to have toxic effects.”

In other words, small changes in your liver health can cause normal doses of everyday medications to become toxic.

Lifestyle changes to care for your liver

If you notice these early signs talk to a trusted health professional. If, knock on wood, everything’s fine, is there anything you can do to avoid it and support your liver?

The answer is yes!

Doctors recommend a combination of lifestyle changes that can do wonders for a fatty liver, including:

  • Losing weight – According to Wynne Armand, MD, writing for Harvard, losing just five percent of your body weight could reduce the level of fat in your liver.
  • Getting your exercise – Aerobic exercise is acknowledged to be one of the best ways to decrease the fat level in your liver. And if you add in a high-intensity workout, it could also reduce inflammation in the organ.
  • Adding in resistance training – Studies have found that resistance training helps reduce both liver fat and unhealthy liver enzyme levels.
  • Eating more protein – Adding more protein to your diet has been shown to help boost both weight loss and fat loss in the liver.

Finally, be sure to give your liver the nutrients it needs to get back on track. Some of the best nutrients to keep your liver health in line include:

  1. N-Acetyl Cysteine (NAC) – To help support gentle detoxification and guard against future damage.
  2. Milk Thistle – A liver booster that promotes the elimination of heavy metal build-up, medication residue, environmental pollutants and alcohol.
  3. Turmeric – A powerful antioxidant to promote healthy liver function and the health of liver cells.
  4. Alpha Lipoic Acid (ALA) – A potent antioxidant to help keep fats from accumulating in the liver.
  5. Selenium – To help promote detoxification and rid the body of toxic mercury buildup.
  6. Schisandra – Helps activate enzymes in the liver cells that produce glutathione – the master antioxidant that detoxifies the body and recycles vitamins C and E, so they can protect cells from free radicals.

Fatty liver is on the rise. Be aware of the sneaky signs that your liver could be in trouble and start taking steps now to keep it trim and healthy.

Editor’s note: Did you know that when you take your body from acid to alkaline you can boost your energy, lose weight, soothe digestion, avoid illness and achieve wellness? Click here to discover The Alkaline Secret to Ultimate Vitality and revive your life today!

Sources:

12 causes of swollen ankles — Medical News Today

Fatty liver disease: What it is and what to do about it — Harvard Health Publishing

Recognizing The Early Symptoms Of Liver Disease – Alcoholic And Non-Alcoholic — Family First Intervention

Importance of fatigue and its measurement in chronic liver disease — NCBI

Insomnia and Liver Disease — Liver Directory

Sleep disturbances in patients with liver cirrhosis: prevalence, impact, and management challenges — NCBI

Caffeine and metabolism — Coffee & Health

Case Study: What does a fatty liver have to do with hot flashes? — Liver Doctor

Effects of Liver Disease on Drug Metabolism — Merck Manual

Categories
Healthy Diet Hormone Health Inflammation Men’s Health Sexual Health Thyroid Health

Ultra-processed foods: A metabolic and hormonal disaster for men

Ultra-processed foods: A metabolic and hormonal disaster for men
Mature adult man with depression sitting on sofa at home

Ultra-processed foods are bad for you. If you’ve heard us say this once, you’ve heard it a thousand times.

Not only do they increase your risk of developing heart disease and 30 other health conditions and diseases, but they’re also behind the obesity epidemic.

In fact, I wrote about the research that confirmed it’s these foods, not lack of exercise — as previously thought — that’s fueling rising rates of obesity.

But what’s truly disturbing is their impact on reproductive and metabolic health…

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Weight gain is just the beginning

A 2025 study at the University of Copenhagen has confirmed that no matter how little of them you eat, ultra-processed foods lead to weight gain.

Researchers compared the health effects of an unprocessed vs. an ultra-processed diet on the same person, in order to get the most accurate results.

Forty-three men spent three weeks eating each of the two diets, with a cleansing period in between.

The unprocessed and ultra-processed diets had the same amount of calories, protein, carbs, and fats. But half the men were given an extra 500 calories per day.

Regardless of whether those extra 500 calories were involved, men on the ultra-processed diet gained about 1 kg (just over 2 pounds) more fat mass than those on the unprocessed diet.

But it doesn’t end there…

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“Our results prove that ultra-processed foods harm our reproductive and metabolic health, even if they’re not eaten in excess. This indicates that it is the processed nature of these foods that makes them harmful,” says Jessica Preston, lead author of the study.

Men on the ultra-processed diet showed:

  • An increase in levels of phthalate cxxMINP, a hormone-disrupting chemical typically found in plastics.
  • A decrease in testosterone and follicle-stimulating hormone, both essential for sperm production. In addition to affecting fertility, low sperm count impacts a man’s sex drive and can be a cause of erectile dysfunction.
  • An increase in LDL (“bad” cholesterol) levels.
  • Altered thyroid hormones.
  • Altered markers of systemic inflammation and oxidative stress.

And in case you’ve forgotten, chronic inflammation causes the cellular damage behind a range of diseases from cancer to Parkinson’s disease to diabetes, not to mention an accelerated aging process that makes your body old before its time.

“We were shocked by how many body functions were disrupted by ultra-processed foods, even in healthy young men. The long-term implications are alarming and highlight the need to revise nutritional guidelines to better protect against chronic disease,” says the study’s senior author, Professor Romain Barrès.

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The choice is clear

I hope you don’t need any more convincing.

Whole foods are the best alternatives to ultra-processed foods. But for success, ease into eating more of them and fewer ultra-processed foods.

Ultra-processed foods are made to “hook” you, so don’t blame yourself if it’s hard to let them go. That being said, see about ditching the two ultra-processed foods considered the worst ASAP.

According to Heartfoundation.org, whole foods and minimally processed foods, like these, are what we all should be eating:

  • Fresh, frozen and canned vegetables and fruit
  • Dried, canned and frozen beans and legumes like lentils and chickpeas
  • Whole grains like oats, brown rice, barley and quinoa
  • Fresh and frozen poultry and meat
  • Fresh, frozen and canned fish and seafood
  • Milk and plain yoghurt (try sweetening with honey)
  • Eggs
  • Nuts and seeds.

An easy way to identify ultra-processed foods is that they are quick, easy, and require little to no preparation — the very definition of “convenience foods.”

They include foods like sweetened cereals, soda and white bread; frozen French fries, chicken nuggets and pizza; processed meats, like hot dogs and bacon; pre-packaged baked goods, like cookies and cakes; and microwaveable meals.

Make the choice today and start taking back your health and your longevity.

Editor’s note: There are perfectly safe and natural ways to decrease your risk of blood clots including the 25-cent vitamin, the nutrient that acts as a natural blood thinner and the powerful herb that helps clear plaque. To discover these and other secrets of long-lived hearts, click here for Hushed Up Natural Heart Cures and Common Misconceptions of Popular Heart Treatments!

Sources:

Why ultra-processed diets make you gain fat even without extra calories — Science Daily

Effect of ultra-processed food consumption on male reproductive and metabolic health — Cell Metabolism

Here’s What Eating Processed Foods for Two Weeks Does to Your Body — Time

Five ways to eat less processed food — Heart Foundation

Categories
Health News Healthy Living Immune System

The little gland that’s key to a lifetime of good health

Thymus The little gland that’s key to a lifetime of good health
A woman is closing her eyes, doing breathing exercise and meditating in nature.

Chances are you’ve heard of glands like the thyroid and adrenals. But we don’t hear nearly enough about an odd little organ located deep in the chest, close to the heart. This organ is the thymus gland.

It produces several hormones like thymulin and thymosin, which regulate immune cell production. It also synthesizes hormones such as insulin and melatonin.

But its central function is to produce and release powerful immune cells to help fight infection and disease.

Most experts believed, however, that the thymus’ contributions occurred in the womb and didn’t extend into adulthood.

But investigators have found that theory was wrong.

In fact, they believe the thymus may hold the secret to a lifetime of good health, thanks to a specialized kind of cell they hope to harness for future preventative treatments…

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The education of T cells

A team of Australian researchers examined thymus samples donated to the Melbourne Children’s Heart Tissue Bank from heart surgery patients up to 16 years old. They likely chose these samples because the thymus is most active in childhood.

The researchers looked at the role of gamma delta T cells within the gland and found for the first time how the organ produced these cells.

“We have large numbers of these specialized cells in our blood and tissues, which accumulate as we become adults,” says study co-author Dan Pellicci, a professor at the University of Melbourne. “Until our study, it was unclear how these cells develop in the body.

Similar to receiving an elementary, high school and college education, the T cells are trained over three stages and fully form in the thymus, Pellicci says.

“Following this education, the cells are ready to enter the rest of the body and are completely capable of fighting infections,” he adds.

Some previous studies suggested these immune cells were mainly derived in the liver and thymus during fetal development in the womb.

“Many experts assumed that after birth, the thymus played little role in the development of these cells as we age, but we now know this little unsung organ helps the body prepare for a lifetime of good health,” Pellicci says.

The hope is that through understanding their function, these T cells can be manipulated to help prevent cancer and highly infectious diseases such as COVID-19 and tuberculosis.

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The care and feeding of this important gland

It’s clear the thymus gland is a key part of our immune system. Unfortunately, the thymus tends to shrink with age, and by the time we hit the age of 65, it’s pretty much unable to produce any new T cells.

This explains why older people are at higher risk for a lot of diseases like cancer, and why they have a harder time fighting off infections.

The good news is there are a few things you can do to support it:

  • Get more antioxidants. One study found that antioxidants — especially vitamin C — can protect the thymus from damaging free radicals and prevent some of that age-related thymus shrinkage.
  • Cut down on wheat. Research has shown that a chemical in wheat called wheat germ agglutinin (WGA) contributes to a shrinking thymus.
  • Get enough zinc. It’s the most important mineral your thymus needs to stay healthy. Correcting a zinc deficiency can prompt the thymus to grow and start generating T cells again.
  • Don’t use artificial sweeteners. Studies have found artificial sweeteners like sucralose shrink the thymus gland in rats.
  • Try tapping. It’s not scientifically proven (yet), but tapping your chest over your thymus gland can supposedly stimulate a sluggish immune system. Try tapping the center of your chest, below your collarbone, for 15 to 20 seconds several times per day. Hum as you do it for even better results.

Editor’s note: Are you feeling unusually tired? You may think this is normal aging, but the problem could be your master hormone. When it’s not working, your risk of age-related diseases skyrockets. To reset what many call “the trigger for all disease” and live better, longer, click here to discover The Insulin Factor: How to Repair Your Body’s Master Controller and Conquer Chronic Disease!

Sources:

Discovery could lead to more treatments to prevent cancer and infectious diseases — ScienceDaily

A three-stage developmental pathway for human Vγ9Vδ2 T cells within the postnatal thymus — Science Immunology

What is the thymus gland? — Medical News Today

Categories
Brain Health Health News Sugar Sweeteners

Why diet drinks can prematurely age your brain

Why diet drinks can prematurely age your brain
Customer in a restaurant having a carbonated beverage

Artificial sweeteners like aspartame and saccharin provide the sweetness of sugar without the calories. And if you have diabetes, you can consume these sweeteners without spiking your blood sugar.

Sounds perfect, right?

Not exactly.

What good is losing weight and looking trim if your memories are slowly being erased?

Take a look at the newest research on artificial sweeteners and what they do to your cognitive abilities…

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Artificial sweeteners steal your brain power

A large Brazilian study has found that the most common artificial sweeteners — those found in diet sodas, flavored waters, and processed snacks — are strongly associated with a decline in memory and loss of cognitive skills.

The study looked at seven low- and no-calorie sweeteners. You’ve probably seen some of these on your soda, chewing gum, or snack labels:

  • aspartame
  • saccharine
  • acesulfame-K
  • erythritol
  • xylitol
  • sorbitol
  • tagatose

The study followed 12,772 adults for an average of eight years. At the start, participants completed questionnaires about what they ate and drank during the past year. They were then broken up into three groups based on the total amount of artificial sweeteners they’d consumed.

All participants were given cognitive tests at the start, middle, and end of the study to track memory, language, and thinking skills over time. These tests looked at things like verbal fluency, working memory, word recall, and processing speed.

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People who consumed the highest amount of these sweeteners showed a 62 percent faster decline in overall thinking and memory skills than those who consumed the lowest amount — the equivalent of 1.6 years of extra brain aging.

Just to give you some perspective, for aspartame, a common sweetener, the highest amount was equal to drinking just one can of soda per day!

Other findings:

  • People under the age of 60 who consumed the highest amounts of sweeteners showed faster declines in verbal fluency and overall cognition.
  • The link to faster cognitive decline was stronger in participants with diabetes than in those without diabetes.

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Alternatives to artificial sweeteners

This isn’t the first time the alarm has sounded about the impact of artificial sweeteners on cognition.

In 2017, a study at Boston University found that people who drank diet soda daily were almost three times as likely to develop stroke and dementia when compared to those who did not.

In case you’re not already convinced to give up those diet sodas, here are some other scary things that artificial sweeteners can do to you:

Fortunately, there are healthier alternatives to sweetening your food and drink. And if you don’t overdo it, there’s no need to worry about the calories.

  • Honey – known for its antioxidant and antibacterial properties
  • Maple syrup – contains manganese and potassium, and has a lower glycemic index
  • Coconut sugar – made from the sap of the coconut palm
  • Stevia – a plant-based sweetener with no calories and no effect on blood sugar
  • Monk fruit – a natural sweetener with a sweetness level 300 times higher than sugar, and no calories or carbohydrates

So if you’re looking to stay healthy by losing those extra pounds, make sure you don’t lose your mind power, too.

Editor’s note: What do you really know about stroke? The truth is, only 10% of stroke survivors recover almost completely, and all doctors can offer is what to do after a stroke occurs. That’s unacceptable considering 80% of strokes are preventable! Click here to discover how to escape The Stroke Syndrome: 5 Signs it’s Stalking You — Plus the Hidden Causes and Preventive Measures You’ve Never Heard About!

Sources:

Sweeteners in diet drinks may steal years from the brain — Science Daily

Association Between Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline — Neurology

Categories
Blood Pressure Healthy Aging Oral Health

The missing link for lower blood pressure with beet juice

The missing link for lower blood pressure with beet juice
Fresh and healthy beetroot juice, good for the hart and blood pressure

You may have read about the link between beets and heart health — particularly blood pressure.

In fact, several studies have shown that consuming beet juice can lower blood pressure in both healthy individuals and those with high blood pressure.

One reason is that beets are loaded with nitrates. The body converts nitrate into nitric oxide (NO), a signaling molecule that’s vital for the healthy functioning of blood vessels and, in turn, the regulation of blood pressure.

However, new research suggests there may be a caveat to this effect — particularly in younger adults…

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The role of the oral microbiome

A study by researchers at the University of Exeter in the U.K. recruited 39 adults under the age of 30, as well as 36 adults in their 60s and 70s. For two weeks, each group took a concentrated “shot” of beet juice twice a day. After a two-week reset period, participants consumed a placebo version of beet juice with the nitrate removed twice daily for two weeks.

The results were surprising. While the older adults saw a noticeable decrease in blood pressure after drinking the nitrate-rich beet juice for two weeks, the younger adults did not. No change was observed in either group after drinking the beet juice with nitrate removed.

“We know that a nitrate-rich diet has health benefits, and older people produce less of their own nitric oxide as they age,” says study author Anni Vanhatalo, a professor at the University of Exeter. “They also tend to have higher blood pressure, which can be linked to cardiovascular complications like heart attack and stroke.”

It’s known that an imbalance between beneficial and harmful oral bacteria can reduce the conversion of nitrate to nitric oxide. This prompted the researchers to use a gene sequencing method to analyze which bacteria were present in the mouth before and after each two-week period.

They made a fascinating discovery…

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While there were significant changes in the oral microbiome in both groups after drinking the nitrate-rich beet juice, the changes differed between the younger and older groups.

The older age group showed a notable decrease in the mouth bacteria Prevotella after drinking the unaltered beet juice with nitrate, as well as an increase in the growth of beneficial bacteria such as Neisseria. The younger group showed an increase in some beneficial bacteria, including Neisseria, but not to the same extent as the older group.

In short, the blood pressure-lowering effect of nitrate-rich beet juice in older people may be enhanced due to specific changes in their oral microbiome.

“This study shows that nitrate-rich foods alter the oral microbiome in a way that could result in less inflammation, as well as a lowering of blood pressure in older people,” says co-author Andy Jones, a professor at the University of Exeter. “This paves the way for larger studies to explore the influence of lifestyle factors and biological sex in how people respond to dietary nitrate supplementation.”

A previous study by the University of Exeter found that beet juice promoted healthier aging in just 10 days.

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Make the most of what beet juice can do

Dr. Lee Beniston of BBSRC says the study “opens up new opportunities for improving vascular health through nutrition.”

“Encouraging older adults to consume more nitrate-rich vegetables could have significant long-term health benefits,” Vanhatalo says. “The good news is that if you don’t like beetroot, there are many nitrate-rich alternatives like spinach, rocket, fennel, celery and kale.”

While it’s true that you can get nitrates from these other vegetables, you would have to eat a significant amount of them to obtain the same benefits as you would from a glass of beet juice.

That’s why most studies on dietary nitrate and heart health have used beet juice and beet powders, which are popular among athletes.

I’m not a big beet fan, but there are ways to make them more palatable. For instance, if you make your own beet juice with a blender or juicer, you can add celery, cucumber or apple for additional flavor. But nothing is easier than a pre-made beet powder you can mix with water or juice.

It’s essential to note that certain dental hygiene habits can affect the natural processes that facilitate the conversion of nitrates to nitric oxide.

Researchers at Baylor College of Medicine and the University of Texas found that antiseptic mouthwash, particularly that containing chlorhexidine, interfered with that conversion process and led to a significant increase in systolic blood pressure in a group of 26 study participants.

Editor’s note: What do you really know about stroke? The truth is, only 10% of stroke survivors recover almost completely, and all doctors can offer is what to do after a stroke occurs. That’s unacceptable considering 80% of strokes are preventable! Click here to discover how to escape The Stroke Syndrome: 5 Signs it’s Stalking You — Plus the Hidden Causes and Preventive Measures You’ve Never Heard About!

Sources:

Beetroot juice lowers blood pressure in older people by changing oral microbiome — University of Exeter

Ageing modifies the oral microbiome, nitric oxide bioavailability and vascular responses to dietary nitrate supplementation — Free Radical Biology and Medicine

Categories
Heart Health Menopause Women’s Health

The menopause link to 40% of deaths in women

The link between menopause and 40% of all deaths in women
blonde young female in sweater feel fatigue, asthma attack or dyspnea at home. illness girl with headache and cardiac pain

Menopause is a time of hot flashes, night sweats, mood swings, bloating, fatigue, thinning hair and other uncomfortable and downright irritating symptoms.

But even worse, for some women, the transition can also mean that higher risks for heart attack and stroke are just around the corner.

Now, researchers from the University of Texas Southwestern Medical Center have discovered just how menopause is linked to the number one killer of women.

The good news is that, by understanding the risks, women everywhere can have a better shot at a long, heart-healthy life.

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Your heart on menopause

Many people still think of cardiovascular disease as “a man’s disease.” But in truth, it’s the biggest killer of women, responsible for approximately 40 percent of all deaths.

Research has already shown that the risk of heart disease in women rises sharply after menopause.  Though it’s not been clearly understood why. However, we do know that negative changes in blood fats (or lipids) may play a role since they tend to occur during the perimenopause period.

Sadly, scientists had only looked into the most basic lipid tests in women (think LDL, known as bad cholesterol, HDL or good cholesterol and triglycerides), so we haven’t had all the facts.

Luckily, that’s changed thanks to a Texas research team that delved into advanced lipid problems in menopausal women, including what are known as lipid subfractions and particle numbers, which have shown to be far better at predicting cardiovascular disease.

Advanced tests reveal threat to menopausal hearts

The researchers performed these top-tier blood tests on over 1,240 pre-, peri- and post-menopausal women and another 1,340 plus men for comparison.  They then followed up for approximately seven years.

What they discovered was this:

  • A big increase in “bad cholesterol.” All three female groups had an increase in LDL-P (the number of bad cholesterol particles) compared to men but the greatest percent change was found to be between peri and post groups at 8.3 percent. LDL-P is a hidden risk for cardiovascular disease.
  • A loss of “good cholesterol.” Compared to men, post-menopausal women had the greatest percent change of HDL-P (the number of good cholesterol particles) with a negative change of 4.8%.  When HDL-P count is low, you are trending towards insulin resistance and a greater risk of heart attack and stroke.
  • Negative changes for blood vessels. Small-dense LDL had a greater percent change in the peri-menopausal group when compared to men with a change of 213%. This percent change is ~15% higher than both pre- and post-menopause groups.  Smaller LDL-P size can more easily enter the blood vessel wall and cause heart disease. Worse, small dense LDL can more easily get into the artery wall, leading to arteriosclerosis.

“We found that menopause is associated with adverse changes in lipoprotein profiles, with the most pronounced changes found to be in increases in ‘bad’ LDL-particles and subfractions observed for peri-menopausal women,” said study author Dr. Stephanie Moreno. “When looked at together, these changes could help explain the increase of cardiovascular disease in post-menopausal women and help determine if earlier interventions are warranted.”

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Be proactive about your heart risks

One out of three U.S. adults has some form of heart disease. Yet, approximately 50% of people who experience a heart attack have “normal” cholesterol results.

So if you’ve made the transition to menopause or soon will, ask your doctor about these advanced blood tests. It makes sense to use the most accurate and predictive testing for risk assessment — especially now that we know the transition to menopause can drive your lipid values into the danger zone.

It also makes sense to stay on top of the latest developments about women’s heart health. For example, scientists have found that beets can give back some of the heart protection that menopause steals…

In experiments with postmenopausal women who drank beetroot juice, researchers saw such improvements in blood flow, they determined if the level of improved blood-vessel function could be maintained over the postmenopausal years — it could significantly reduce the risk to women’s heart health.

Why beetroot juice?

When a woman’s estrogen production tanks, so does the level of nitric oxide (NO) normally produced by her body. Beets help ramp it back up. NO is a signaling molecule in the endothelial cells that line the walls of our arteries. NO functions as a powerful vasodilator and an important regulator of the cardiovascular system.

Editor’s note: There are perfectly safe and natural ways to decrease your risk of blood clots including the 25-cent vitamin, the nutrient that acts as a natural blood thinner and the powerful herb that helps clear plaque. To discover these and other secrets of long-lived hearts, click here for Hushed Up Natural Heart Cures and Common Misconceptions of Popular Heart Treatments!

Sources:

Menopause potentially linked to adverse cardiovascular health through blood fat profile changes — EurekAlert!

Associations Between High-Density Lipoprotein Particles and Ischemic Events by Vascular Domain, Sex, and Ethnicity: A Pooled Cohort Analysis — Circulation

Categories
Health News Healthy Living Immune Health

Over-the-counter drugs that supercharge antibiotic resistance

Over-the-counter drugs that supercharge antibiotic resistance
Woman pouring pills from bottle into her hand

According to the CDC, the level of antibiotic resistance has grown to epidemic proportions.

In fact, in the U.S. alone, more than 2.8 million antibiotic-resistant infections occur every year, with new forms of resistance emerging at an accelerated pace.

You probably already know that the antibiotics used to fight bacterial infections can actually contribute to this resistance over time, especially when taken too frequently, when not finished as directed by a doctor, or when taken for conditions where antibiotics have no effect — viruses, for example.

But what you may not know is that other common medications are fueling the problem.

Two of the worst are likely in your medicine cabinet right now…

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The perfect conditions for resistant bacteria to thrive

Researchers from the University of South Australia have demonstrated that ibuprofen and acetaminophen not only drive antibiotic resistance when used individually, but also amplify it when used in combination.

In fact, their research showed that when taking these medications, along with the broad-spectrum antibiotic ciprofloxacin for E. coli (a common bacterium that causes gut and urinary tract infections), the drugs made the bacteria highly resistant to the antibiotic.

“When bacteria were exposed to ciprofloxacin alongside ibuprofen and acetaminophen, they developed more genetic mutations than with the antibiotic alone, helping them grow faster and become highly resistant. Worryingly, the bacteria were not only resistant to the antibiotic ciprofloxacin, but increased resistance was also observed to multiple other antibiotics from different classes,” observed lead researcher and associate professor, Rietie Venter.

According to scientists, taking Tylenol or ibuprofen actually activates the bacteria’s defenses, allowing them to expel the antibiotic and creating conditions that enable the bacteria to thrive.

Combat antibiotic resistance through wellness

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As the researchers point out, “Antibiotic resistance isn’t just about antibiotics anymore.”

And considering this is just one more antibiotic resistance threat in what seems to be an ever-growing list, it’s also one more reason why it’s vital to support your body’s natural immune response.

The key is to make sure that the response is balanced.

I say that because an immune response can be a double-edged sword. While an underactive response leaves the body open to illness, an overactive immune system cannot distinguish between the body’s own systems and invaders.

There are a few ways to help support your immune system so it’s up to the task…

Vitamin D3: A study published in the Frontiers of Immunology confirmed significant differences between the two types of vitamin D, with vitamin D2 having a questionable impact on human health. However, the study found that vitamin D3 could balance people’s immune systems by tamping down inflammatory response, and help strengthen defenses, even against viral infections.

Black seed or black seed oil: The black seeds of the Nigella sativa plant contain a compound called thymoquinone, considered to be an “immune system modulator,” meaning it promotes a balanced response.

Exercise: A 2005 study published in the journal Medicine and Science in Sports and Exercise revealed that walking briskly for 30 minutes increased the number of natural killer cells, white blood cells and other important immune cells circulating in the body.

Thymus gland support: This gland is a key part of our immune system. Unfortunately, the thymus tends to shrink with age, and by the time we reach the age of 65, it’s largely unable to produce new T cells. But you can find ways to support it here.

When you do get a sickness that requires antibiotics, consider taking fish oil supplements with them. Research led by Flinders University discovered that omega-3 fatty acids, like those found in fish oil, can break down the ability of superbugs to become resistant to antibiotics.

Editor’s note: Regain your health and enjoy a full, vibrant life by defeating the real culprits of premature aging and sickness — excessive, damaging acid in your body! The truth is when you’re alkaline, wellness thrives and sickness takes a dive. Click here to discover The Alkaline Secret to Ultimate Vitality!

Sources:

Common painkillers like Advil and Tylenol supercharge antibiotic resistance – ScienceDaily

Antimicrobial Resistance Facts and Stats – CDC

Categories
Health News Healthy Diet Healthy Living Urinary Tract Health

The food that may give you an antibiotic-resistant UTI

Woman with UTI

Trying to eat healthier?

Then I’d venture to guess chicken is one of your go-to protein sources.

One of the healthiest diets around — the Mediterranean diet — encourages people to get most of their protein from lean sources like chicken and fish. So, chicken finds its way onto the plates of health-conscious people.

The problem is, chicken isn’t just a healthy source of lean protein. It’s a breeding ground for bacteria.

You probably know that you have to be extra careful when handling raw chicken — even more cautious than when you handle other types of meat.

Part of the reason is that dangerous bacteria like Salmonella, Campylobacter and E. coli are present in chicken while they’re alive, and stick around even after the bird is processed for sale in a supermarket.

If chicken is cooked at a high enough temperature, that should be enough to ensure your chicken is safe to eat.

However, it appears that even if you think you’re cooking your chicken thoroughly and don’t end up with food poisoning, these dangerous bacteria can still find their way into your body and cause an extremely uncomfortable, and often resistant, health problem…

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E.coli: The cause of resistant and recurrent urinary tract infections

A few years ago, researchers from the University of California, Berkeley and the U.S. Centers for Disease Control and Prevention had a nagging suspicion about the poultry on our plates.

They thought it could be bringing dangerous bacteria into our bodies that eventually end up in the urinary tract and potentially the bladder, too.

They first began piecing together the connection between chicken and urinary tract infections (UTIs) after noticing that, in previous research, antibiotic-resistant UTIs were typically caused by a particular strain of E. coli related to the E. coli found in chicken.

“When we compared the fingerprints of the E. coli from the poultry and the human UTI cases, we found there’s an overlap of some genotypes,” said study author Dr. Lee Riley, a professor of infectious disease at Berkeley’s School of Public Health.

Since those findings in 2017, the treatment of UTIs has become complicated. Today, many of the E. coli strains behind UTIs have become resistant to multiple drugs, including fluoroquinolones like ciprofloxacin and levofloxacin.

A 2024 study found that patients with recurrent UTIs had higher rates of resistance and noted that resistance increases with subsequent infections.

It’s an uncomfortable and dangerous situation… one that could put your life in jeopardy. An untreated UTI, after all, can spread to your kidneys and even your bloodstream.

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How E. coli infects the urinary tract, and how to avoid it

It’s not an uncomfortable conversation, but we need to talk about how E. coli from chicken can make it into someone’s urinary tract.

They suspect that people who end up with these infections are either eating chicken that hasn’t been handled correctly in the kitchen or cooked thoroughly enough to kill the bacteria.

Of course, washing hands is paramount before cooking or handling food, but washing them after handling raw meat is just as important. When cooking chicken, ensure the meat has no pink tint (use a food thermometer to verify the chicken’s internal temperature is at least 165°F).

Still, how does the E. coli make it to the urinary tract?

Anatomy is the reason women are more prone to UTIs — though men have plenty of ways to end up with painful UTIs, too. But in women, the urethra, which carries urine from the bladder to exit the body, is typically shorter — and it’s in very close proximity to the anus.

This is the reason women grow up hearing the mantra “wipe front to back.” If you don’t wipe front to back, and you’ve ingested E. coli, it’s possible to bring the bacteria up from the anus to the urethra, where they can invade the urinary tract.

Prevention is the best medicine when it comes to antibiotic-resistant infections. Cranberry juice, already popular as a remedy, recently had its credibility backed by science. That’s why it’s included in this three-part system my friend Dr. Adria Schmedhorst shared, that could help you keep the threat of recurrent UTIs at bay.

Editor’s note: Did you know that when you take your body from acid to alkaline you can boost your energy, lose weight, soothe digestion, avoid illness and achieve wellness? Click here to discover The Alkaline Secret to Ultimate Vitality and revive your life today!

Sources:

  1. Did your urinary infection come from a chicken coop? — MedicalXpress. Retrieved October 12, 2017.
  2. The Science of Why Chicken Goes Bad So Quickly — Gizmodo. Retrieved October 12, 2017.
  3. Study Finds Kosher Chicken Has Highest Rate of Antibiotic-Resistant E. Coli — Food Safety News. Retrieved October 12, 2017.
  4. How to prepare and cook chicken safely — The Telegraph. Retrieved October 12, 2017.
  5. Chicken from Farm to Table — United States Department of Agriculture. Retrieved October 12, 2017.
Categories
Anti-Aging Fitness & Exercise Longevity

Doing this regularly could help you age in reverse

Doing this regularly could help you age in reverse
Carefree mid adult woman with long red hair wearing casual clothes is dancing and smiling at home in the living room, celebrating and enjoying life

Most of us think of our age as the number of years we’ve spent on this earth.

But there’s another measurement of age that has a far bigger impact…

Known as epigenetic or biological age, it presents a more accurate picture of how well your body’s cells and tissues are functioning. That makes it a more precise measure of age and risk for age-related disease.

The good news is that there are ways to slow down the epigenetic aging process and push back the onset of aging-related diseases, potentially increasing both your healthspan and lifespan.

And research has revealed one of the simplest and most effective ways to reverse your body’s aging clock is something you can do right now…

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Delivering measurable reductions in biological age

In research from Tohoku University, scientists reviewed existing evidence from studies showing that regular exercise, physical activity and fitness may influence epigenetic aging and potentially reverse it.

The results were compelling enough that you may just want to get up and dance — or walk, run, lift weights, go swimming, or engage in any type of exercise that floats your boat.

That’s because the deep dive into study after study revealed the incredible benefits of staying active for reducing epigenetic aging, including:

  • A study in mice that demonstrated that endurance and resistance training reduced age-related molecular changes in muscle tissue.
  • A human study that found exercising reduced biological age markers in blood and skeletal muscle.
  • Research that revealed that sedentary middle-aged women could reduce their epigenetic age by two years after just eight weeks of combined aerobic and strength training.
  • Another study that found older men with higher oxygen uptake levels, a key measure of cardiovascular fitness, had significantly slower epigenetic aging.

According to the scientists, “These findings suggest that maintaining physical fitness delays epigenetic aging in multiple organs and supports the notion that exercise as a geroprotector confers benefits to various organs.”

Considering all that can go wrong without exercise, I’m not really surprised.

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Which organs benefit most?

The research also was able to show that while exercise is excellent for slowing aging across your entire body, specific organs grab even bigger benefits.

Obviously, exercise offers benefits for your skeletal muscles, which are used to move your body as you exercise, allowing them to stay strong and healthy.

However, beyond muscle, regular physical training may also slow the aging process in your heart, liver, fat tissue, and even your gut (which controls a significant portion of your immune system).

The scientists do say, though, that if you want to experience to the fullest extent the anti-aging benefit exercise can deliver, the key is to leverage a structured exercise routine that is planned, repetitive and goal-directed.

That’s because regular exercise, like riding an exercise bike, playing tennis, going for a jog or lifting weights, appears to have more potent effects on slowing epigenetic aging than general physical activity, such as walking or doing household chores.

In addition to exercise, restricting calories can also help reduce aging and even mortality risk. So you have choices. Do what feels right for you.

Editor’s note: Are you feeling unusually tired? You may think this is normal aging, but the problem could be your master hormone. When it’s not working, your risk of age-related diseases skyrockets. To reset what many call “the trigger for all disease” and live better, longer, click here to discover The Insulin Factor: How to Repair Your Body’s Master Controller and Conquer Chronic Disease!

Sources:

Exercise may actually reverse your body’s aging clock – ScienceDaily