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6 worst medications for your kidneys (slideshow)
Antibiotics
Renal tubular cells are key players in kidney filtration, making them particularly vulnerable to toxic effects that drugs may expose them to. Tobramycin, from the antibiotic class known as aminoglycosides, can cause higher toxicity to the filtration cells.
Antimicrobial medications known as sulfonamides (thiazide diuretics, acetazolamide, sulfonylureas and some COX-2 inhibitors), can promote swelling and inflammation of the kidneys due to crystals they create that the kidneys can’t dissolve.
If you must take antibiotics on occasion, make sure you know how to take them safely.