The Best Supplements For Detox And A Healthier Heart

While EDTA chelation moves calcium out of the arterial lining in order to improve blood flow, it also removes heavy metals out of your body such as aluminum, cadmium, mercury and lead. Also, chelation to improve cardiovascular health can be achieved by other safe nutrients besides EDTA. I’ll discuss these and other nutrient supplements that improve blood flow for improved health and longevity.

EDTA Chelation Removes Toxic Metals

Previously, I discussed the fact that chelation with EDTA in IV and oral forms represents one way to improve cardiovascular health. Did you also know it causes your body to excrete minerals which are unquestionably toxic? Toxic metals contribute to autoimmune diseases and the underlying inflammation process of chronic illness, including heart disease. Consider the fact that lead is toxic to your brain and nerves. Even a slightly increased lead level raises your chance of death by 46 percent. In a 2002 article in Archives of Internal Medicine, researchers reported that 4,292 individuals age 30 to 74 years were found to have slightly elevated blood lead levels. Among these people with slightly elevated levels, there was a 46 percent increased death rate (all-cause mortality) during the study compared to those with completely “normal” blood lead levels.

At the University of Michigan, a small study of the effect of one dose of an oral EDTA chelation product on 14 patients ages 29 to 73 showed excretion of the heavy metals by the following amounts:

  • Aluminum: 229 percent
  • Arsenic: 661 percent
  • Cadmium: 276 percent
  • Lead: 350 percent
  • Mercury: 773 percent
  • Nickel: 9,439 percent

During the chelation process, you may lose some beneficial trace elements, such as zinc and calcium, along with the toxic ones I’ve listed. However, with a diet of adequate fresh vegetables or even taking a zinc and calcium supplement, you can easily offset this.

More good news: EDTA appears not to deplete the trace minerals cobalt, chromium and copper; and it even helps retain the beneficial trace mineral magnesium. [1] Furthermore, EDTA is an amino acid that enhances the absorption of zinc with protein and the amino acids cysteine and methionine. [2]

Chelation Nutrients IP-6 And Vitamin K2

EDTA is not the only chelation method on the market. A food nutrient called inositol hexaphosphate (IP6, or phytate) has been shown to effectively keep calcium out of the arteries and in the bones where it should be. A 2006 study reported in Frontiers in Bioscience showed a highly significant reduction in the calcium content of aorta and heart tissue in rats treated with phytate. [3] In humans it is known that supplementing with 1,000 mg IP6 daily moves calcium out of your arteries while also leaving calcium in your bones where it helps strengthen them; scientific studies show that IP6 helps convey to where it belongs in the skeleton.

A 2008 report published in the Journal of Medicinal Food [4] looked at 1,903 subjects and found that with increasing amounts of IP6 consumption there was increasing bone mineral density (less osteoporosis). A 2012 study confirmed this finding, which was reported in the European Journal of Nutrition.[5] In this study of 157 postmenopausal women, scientists found a strong correlation between high urinary IP6 concentrations and stronger bones of the lumbar spine over 12 months.

In addition to IP6, vitamin K2 (menaquinone) is another nutrient that shows impressive promise. This critical vitamin activates proteins that prevent excess calcium deposition in your blood vessels. [6] [7] The two forms of vitamin K2, MK-7 and MK-4, both “shuttle” calcium out of your bloodstream and into your bones.

Other Supplements For Healthy Heart And Blood Flow

  • L-Arginine: at 6 grams daily triggers the natural arterial secretion of nitric oxide, which dramatically relaxes arterial smooth muscle for optimal blood flow.
  • Nattokinase: nature’s blocker clot buster derived from the Japanese natto bean. Keeps arterial blood flow optimal.
  • Malic acid: Your body manufactures this substance naturally. Apples and grapes contain several hundred milligrams of malic acid. Although not as powerful as EDTA to chelate heavy metals, supplementation with malic acid has also been found to help remove the toxic metals aluminum, lead and strontium. It is thought to be a good addition to EDTA for improving blood flow, too.
  • Magnesium: Interestingly, one study reported in the Journal of Rheumatology showed significant symptom reduction for fibromyalgia patients at the dose of 2,400 mg with 600 mg elemental magnesium daily. [8]
  • Garlic: A natural chelator and also an antioxidant, garlic has the ability to chelate lead and mercury from the body. It is thought to help to lower the sticky cholesterol underlying the atherosclerosis process and help keep your arteries elastic.
  • Alpha lipoic acid: scavenges free radicals and helps to promote arterial flexibility.
  • Grape seed extract: has antioxidant polyphenols and reduces inflammation and oxidative stress markers.
  • N-Acetyl-Cysteine: promotes the production of glutathione, your body’s most prevalent antioxidant and promoter of ATP energy.
  • Folic Acid: This B vitamin, along with vitamins B6 and B12, reduces homocysteine. An elevated homocysteine level is a known risk factor for heart disease.

Editor’s note: Have you heard of EDTA chelation therapy? It was developed originally to remove lead and other contaminants, including heavy metals, from the body. Its uses now run the gamut from varicose veins to circulation. Click here to discover Chelation: Natural Miracle for Protecting Your Heart and Enhancing Your Health!


[1] Waters RS, Bryden NA, Patterson KY, Veillon C, Anderson RA.  EDTA chelation effects on urinary losses of cadmium, calcium, chromium, cobalt, copper, lead, magnesium, and zinc. Biol Trace Elem Res. 2001 Dec;83(3):207-21

[2] Mohamedshah F. Mineral absorption: zinc, selenium, chromium, calcium. Slide presentation at: National Institute of Health Bioavailability Conference; January 5, 2000.

[3] Grases F, Sanchis P, et al. Phytate (Myo-inositol hexakisphosphate) inhibits cardiovascular calcifications in rats. Frontiers in Bioscience January 1, 2006 (11)136-142

[4] A.A. López-González, F. Grases, P. Roca, B. Mari, M.T. Vicente-Herrero, and A. Costa-Bauzá. Journal of Medicinal Food. December 2008, 11(4): 747-752.

[5] Angel A. Lopez-Gonzalez, Felix Grases, et al. Protective effect of myo-inositol hexaphosphate (phytate) on bone mass in postmenopausal women. European Journal of Nutrition 2012, DOI: 10.1007/s00394-012-0377-6.

[6] Fodor D, Albu A, Poantă L, Porojan M.  Vitamin K and vascular calcifications. Acta Physiol Hung. 2010 Sep;97(3):256-66.

[7] Wallin R, Schurgers L, Wajih N. Effects of the blood coagulation vitamin K as an inhibitor of arterial calcification. Thromb Res. 2008;122(3):411-7.

[8] Russell J, Michalek J, Flechas J, et al. Treatment of fibromyalgia syndrome with SuperMalic: A randomized, double-blind, placebo-controlled, crossover pilot study. J Rheumatol 1995;22(5):953-7

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Dr. Michael Cutler

By Dr. Michael Cutler

Dr. Michael Cutler is a graduate of Tulane University School of Medicine and is a board-certified family physician with more than 20 years of experience. He serves as a medical liaison to alternative and traditional practicing physicians. His practice focuses on an integrative solution to health problems. Dr. Cutler is a sought-after speaker and lecturer on experiencing optimum health through natural medicines and founder of the original Easy Health Options™ newsletter — an advisory on natural healing therapies and nutrients. His current practice is San Diego Integrative Medicine, near San Diego, California.