When pain makes you reluctant to move, “exercise more” can sound like impossible advice. But the most comprehensive review of its kind throws out the no-pain, no-gain mantra and says less is more, at least for pain relief.

When your back hurts, advice comes from every direction—and some of it could stand between you and relief. Eight persistent myths can leave you afraid to move, spending money on the wrong fixes or overlooking options that could help.

We tend to think aging wears us down little by little. But your immune system has two turning points when that process speeds up. Here’s what changes your defenses, and how to give them the support they need.

Epigenetic age presents a more accurate picture of how well your body’s cells and tissues are functioning. That makes it a more precise measure of age. And unlike the age indicated on your driver’s license, you can reverse it…

What if your metabolism is waiting for a signal your usual workout isn’t sending? Researchers found a striking difference in how the body responds to exercise—and logging more minutes wasn’t the deciding factor.

Something starts changing in your brain’s memory center around 50. Scientists have uncovered a shift that may help explain why the aging brain becomes more vulnerable, and what steps we can take to protect it.