The surprising connection between chelation, kidney disease and heart disease

Did you know that chronic kidney disease kills more people in the U.S. every year than breast cancer or prostate cancer?

It’s a surprising fact since kidney disease gets far less attention than these other diseases.

But do you know what’s even more surprising? People with kidney disease don’t usually die because their kidneys give way. They die because their hearts do.

When your kidneys stop working, calcium builds up in your arteries. That causes heart disease, which is the leading cause of death for people with kidney disease. But a study from Clemson University shows EDTA chelation (using the amino acid ethylenediamine tetra-acetic acid) could help clear out calcium and reduce that risk…

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Chelation could keep chronic kidney disease from harming hearts

In the study, researchers mimicked chronic kidney disease in mice and then treated them with EDTA infusions. Some received traditional EDTA infusions, while others received EDTA infusions that were delivered with nanoparticles (microscopic particles used to carry other agents into the human body).

The nanoparticle EDTA infusions were able to precisely target calcium deposits without damaging other tissues and causing side effects. Do you know what’s even more exciting?

The calcium deposits didn’t come back up to four weeks after the last injection. So this new form of chelation therapy has serious potential for treating heart disease caused by kidney disease… or anything else for that matter.

After all, most cardiologists don’t use chelation therapy because they believe the risks outweigh the benefits. But this therapy may minimize those risks significantly.

What you need to know about EDTA chelation

Obviously, nanoparticle chelation therapy won’t be available for quite some time, if it ever is. It still needs to be tested on humans. If you’re considering traditional EDTA chelation therapy, there are a few things you should know…

Although many studies from the 1950s until the 1990s show chelation may benefit heart health and potentially benefit conditions where calcium plaque builds up, the FDA and most cardiologists aren’t on board with using chelation for this purpose (read more about the scientific evidence supporting chelation therapy for heart disease).

But chelation is approved as a therapy to remove lead and other heavy metals from the bloodstream. EDTA binds to heavy metals and flushes them from the body via urine.

You should also know that there are two different types of chelation therapy — intravenous (IV) and oral. IV chelation will deliver a higher dose of EDTA. That means there’s a higher risk of side effects.

Of course, IV chelation therapy should always be administered by a doctor.

Now, you may be wondering… what are some of the risks of traditional EDTA chelation therapy?

The risks range from minor things like burning at the IV site, fever, headache, nausea, and vomiting to serious things like abnormally low blood-calcium levels (hypocalcemia), sudden drops in blood pressure, drops in bone marrow counts (bone marrow suppression), heart failure, kidney damage and even death.

But let’s not forget conventional heart treatments are also not without risk. The risks of getting a stent include heart attack, stroke and death.

The most passionate advocates of EDTA suggest its use as a preventative, like healthy lifestyle practices including a healthy diet, exercise vitamins and minerals or supplements.

If you’d like to learn more, check out the book below…

Editor’s note: Have you heard of EDTA chelation therapy? It was developed originally to remove lead and other contaminants, including heavy metals, from the body. Its uses now run the gamut from varicose veins to circulation. Click here to discover Chelation: Natural Miracle for Protecting Your Heart and Enhancing Your Health!


  1. Kidney disease killer vulnerable to targeted nano therapy — EurekAlert!
  2. What Does Chelation Therapy Treat? — Healthline
  3. Chelation therapy for heart disease: Does it work? — Mayo Clinic
  4. Kidney Disease: The Basics — National Kidney Foundation
Jenny Smiechowski

By Jenny Smiechowski

Jenny Smiechowski is a Chicago-based freelance writer who specializes in health, nutrition and the environment. Her work has appeared in online and print publications like Chicagoland Gardening magazine, Organic Lifestyle Magazine, BetterLife Magazine,, and