The quickest way to help dementia-causing proteins thrive

Sleep problems are frustrating…

Not only do they leave you exhausted in your day-to-day life, but they take a toll on your long-term health.

Did you know, for example, that ongoing sleep issues increase your risk of obesity, diabetes, cardiovascular disease, anxiety and depression?

And then there’s the connection between poor sleep and dementia. That one’s a real doozy…

Over the years, numerous studies have shown that a lack of sleep contributes to the development of Alzheimer’s and dementia. And the reason why is alarming…

When you sleep, your brain cleans out amyloid plaques, a sticky buildup that collects on your nerve cells. These plaques are thought to cause Alzheimer’s disease. So when you’re not sleeping enough… well, you can guess what happens. These disease-causing plaques take over your brain.

But, according to the latest research, that’s not the only way sleeplessness triggers the dementia disease process in your body…

Researchers from the University of Wisconsin-Madison recently determined that not only does a lack of sleep contribute to more amyloid plaques in your brain, but it contributes to other biological markers of dementia too…

Sleeplessness feeds scary, dementia-causing proteins

In their study, University of Wisconsin-Madison researchers analyzed the spinal fluid of people with an increased risk of Alzheimer’s disease. These people had an increased risk either because a parent had the disease, or because they carried the so-called Alzheimer’s gene — apolipoprotein E (APOE). But none of them were displaying any symptoms of the disease yet. They all had normal thinking and memory skills.

Researchers asked these study participants about their sleep patterns as well, and compared their responses against their spinal fluid samples. And guess what they found?

People who reported poor quality sleep, more sleep problems and daytime sleepiness not only had amyloid proteins in their spinal fluid, they also had tau protein in their spinal fluid. Tau protein is another culprit behind Alzheimer’s. It collects in the brain and forms tangles that, along with amyloid plaques, are the hallmark of Alzheimer’s disease.

The sleep-deprived study participants also had signs of brain cell damage and inflammation in their spinal fluid.

Yikes! It seems a lack of sleep could be the beginning of a long and devastating Alzheimer’s disease process. But researchers have one word of warning…

They say the connection between dementia and sleep is a chicken and an egg type of scenario…

“It’s still unclear if sleep may affect the development of the disease or if the disease affects the quality of sleep,” said study author Barbara B. Bendlin. “More research is needed to further define the relationship between sleep and these biomarkers.”

Regardless, they’re not giving up hope that improving your sleep could also improve your dementia risk. The question is, how can you change your sleep situation for the better before it’s too late?

Sleeping better… sooner rather than later

There are a wide range of sleep issues that could contribute to your dementia risk — sleep apnea, insomnia, circadian-rhythm disorders — to name a few. The best way to overcome your problem will depend largely on what you’re dealing with. But, in general, you can vastly improve your sleep quantity and quality by:

  • Going to bed at the same time every night. It keeps your circadian rhythm on track.
  • Avoiding brightly lit screens (like your TV, phone, computer or tablet) for at least one hour before bedtime.
  • Avoiding alcohol at night. It disrupts REM sleep.
  • Trying the “sleep diet.”
  • Trying ashwagandha, the sleepy herb that knocks out insomnia.
  • Investing in a sleep mask. It can boost your body’s natural production of melatonin.
  • Popping a melatonin pill 30 minutes before bed. It helps reset an out-of-whack body clock.

Editor’s note: Poor sleep isn’t the only thing that could be stealing your mind: 38.6 million Americans take a single drug every day that robs their brain of an essential nutrient required for optimal brain health. Are you one of them? Click here to find out!


  1. Sleep problems may be early sign of Alzheimer’s.” — Science Daily. Retrieved July 7, 2017.
  2. E. Sprecher, et al. “Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults.” — Neurology, 2017; 10.
  3. Amyloid Plaques.” — Memory Loss & the Brain: The Newsletter of the Memory Disorders Project at Rutgers University. Retrieved July 7, 2017.
Jenny Smiechowski

By Jenny Smiechowski

Jenny Smiechowski is a Chicago-based freelance writer who specializes in health, nutrition and the environment. Her work has appeared in online and print publications like Chicagoland Gardening magazine, Organic Lifestyle Magazine, BetterLife Magazine,, and