The cholesterol-lowering trifecta that supports your heart

We hear a lot about individual nutrients and their benefits, but sometimes, the real magic happens when they work together.

Lowering cholesterol isn’t just about cutting back on high-cholesterol foods or unhealthy fats; it’s about strategically incorporating nutrients that actively work to improve your lipid profile. Fiber, plant sterols, and omega-3s each play unique roles, and when combined, their effects are amplified.

This week, let’s explore the powerful synergy of fiber, plant sterols, and omega-3 fatty acids — a true trifecta for lowering cholesterol and supporting heart health.

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Fiber: The Cholesterol Blocker

Fiber, especially soluble fiber, acts like a sponge in your digestive system, trapping cholesterol and removing it from your body before it has a chance to enter your bloodstream. Research consistently shows that high-fiber diets are linked to lower LDL cholesterol levels and a reduced risk of heart disease.

Foods rich in soluble fiber include:

  • Oats and oat bran
  • Beans and lentils
  • Fruits like apples, pears, and berries
  • Vegetables like Brussels sprouts and carrots
  • Seeds such as chia and flaxseeds

Eating more fiber doesn’t just help with cholesterol — it also supports gut health, stabilizes blood sugar, and keeps you feeling fuller longer. In fact, fiber is key to supporting your microbiome’s ability to make adequate amounts of GLP-1 (the hormone that drives satiety and blood sugar control — and is mimicked by drugs like Ozempic®).  

Plant Sterols: Nature’s Cholesterol Fighters

Plant sterols (also called phytosterols) are natural compounds found in plants that closely resemble cholesterol at a molecular level. Because of this similarity, they compete with cholesterol for absorption in the digestive tract — meaning less cholesterol makes it into your bloodstream. Studies show that consuming just 2 grams of plant sterols per day can reduce LDL cholesterol by as much as 10%.

Foods that contain plant sterols include:

  • Nuts and seeds
  • Whole grains
  • Fruits and vegetables
  • Fortified foods like certain margarines and orange juice

At Step One Foods, plant sterols are a key ingredient in our scientifically formulated products, ensuring you get a clinically meaningful dose with every serving.

Omega-3s: The Heart-Healthy Fat

Omega-3 fatty acids are essential fats that help lower triglycerides, reduce inflammation, and support overall heart function. Unlike fiber and plant sterols, which directly lower cholesterol absorption, omega-3s improve cholesterol balance by increasing HDL (good) cholesterol and reducing harmful blood fats that contribute to heart disease. Omega-3s also possess anti-inflammatory and mild blood thinning properties — which help reduce the risk of acute cardiovascular events (like heart attacks and strokes). 

Sources of omega-3s include:

  • Fatty fish like salmon, mackerel, and sardines
  • Walnuts
  • Flaxseeds and chia seeds
  • Algal oil (a plant-based source of omega-3s)

Bringing It All Together

The best way to lower cholesterol naturally is to incorporate all three of these nutrients into your diet consistently. When you do that, the effects can truly be synergistic. For example, we’ve demonstrated that this nutrient combination can yield nearly 40% LDL reductions (far more than what’s possible with plant sterols alone and essentially equivalent to the expected effects of a drug!).  

Step One Foods is here to make it easy to get started on getting enough of these nutrients into your diet. But you can amp up the Step One Foods effect even further. Here’s what a Perfect Trio day might look like:

  • Breakfast: Oatmeal topped with flaxseeds and berries (or Step One’s Blueberry Cinnamon version).
  • Lunch: A salad with walnuts, chickpeas, and avocado
  • Snack: A Step One Foods bar packed with fiber, omegas and plant sterols
  • Dinner: Grilled salmon with roasted Brussels sprouts and quinoa

Whether or not you require medications for cholesterol, by making fiber, plant sterols, and omega-3s a priority, you’re giving your heart the best possible support for positive outcomes. And with Step One Foods, getting these nutrients in the right amounts has never been easier.

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Dr. Elizabeth Klodas MD, FACC

By Dr. Elizabeth Klodas MD, FACC

"Diet is a major driver of high cholesterol, but instead of changing the food, we prescribe medications. This never seemed logical to me.” Dr. Klodas has dedicated her career to preventive cardiology. Trained at Mayo Clinic and Johns Hopkins, she is the founder and Chief Medical Officer for Step One Foods. Dr. Klodas is a nationally sought out speaker and has an active role at the American College of Cardiology. Her clinical interests include prevention of heart disease and non-invasive cardiac imaging and she has published dozens of scientific articles throughout her career. Dr. Klodas has been featured on CNN Health for her mission to change how heart disease is treated. An independent study performed at leading medical institutions affirmed the ability of Step One Foods to deliver measurable and meaningful cholesterol-reduction benefits in the real world. The results of the trial were presented at the 2018 American Heart Association’s Scientific Sessions. Dr. Klodas has also authored a book for patients, "Slay the Giant: The Power of Prevention in Defeating Heart Disease," and served as founding Editor-in-Chief of the patient education effort of the American College of Cardiology. In addition to her practice and her duties at Step One Foods, she also serves as medical editor for webMD.

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