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Protective psychedelics may rewire the brain following stroke
In the United States, someone suffers a stroke every 40 seconds. And while strokes are the fifth most common cause of death in our country, they also rank as a leading cause of disability due to the damage to the cells and wiring of the brain that survivors are all too often left with.
But researchers have a drug they believe could minimize the damage to the brain that occurs during a stroke — and they are ready to test it.
It’s key, however, that the drug be administered almost immediately. So, with the help of EMTs, stroke victims may be given the hallucinogenic drug DMT (dimethyltryptamine) as they speed in an ambulance on the way to the nearest hospital.
Mirroring the effects of LSD to save the brain from stroke
DMT has the same type of psychedelic effects as illegal options, such as LSD or even psilocybin or “magic” mushrooms. But experts point out that the micro-dose planned for Phase 1 of the trials, though sufficient for conferring potential brain rewiring benefits, should be too small to trigger hallucinations to any of the prospective stroke patients.
So, what is DMT?
It’s a psychoactive compound found in ayahuasca — a drink used in the rituals of traditional shamans in South America for centuries. The psychedelic brew is made from the leaves of the Psychotria viridis shrub and the stalks of the Banisteriopsis caapi vine.
Together, these two plants have a potent effect on the central nervous system that can lead to hallucinations, an altered state of consciousness, euphoria and out-of-body experiences that earned it the nickname, “spirit molecule.”
Over the past decade or so, it’s made its way to the United States as a recreational drug.
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DMT: New brain cells and improved motor function
Past studies looking at rats who have suffered brain damage have demonstrated the ability of DMT to not only improve motor function but even stimulate the formation of brand new brain cells.
And because of this, scientists at Canadian company Algernon Pharmaceuticals believe DMT could be the answer to less brain damage and better function following stroke.
You see, research has shown that following a stroke, the brain will try to rewire itself in order to preserve function — a process that happens within just a few hours of the initial injury.
The Algernon researchers say that with the promising results DMT has shown in rats, it could provide the answer to supporting this process, possibly speeding it up and delivering a faster and more complete recovery for stroke victims.
They hope that DMT can be used to improve neuroplasticity and boost nerve cell growth in the brain -and with it healing.
In Phase 1, they plan to start giving DMT to stroke patients while they’re still on the way to the hospital.
After that?
Algernon hopes that if the first phase of trials prove successful, regulators will approve the more widespread usage of the treatment. In the second and third phases of the trial, Algernon hopes to continue DMT treatments over the short and long term to prove the efficacy of the treatment.
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Sources:
Stroke Facts – CDC
STROKE VICTIMS TO BE GIVEN PSYCHEDELIC DRUG DMT IN FIRST-EVER US CLINICAL TRIALS – Waking Times
By Dr. Adria Schmedthorst
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